Aspirin

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Ray Peat regarded aspirin as one of the most valuable and underappreciated medicines. Beyond its well-known pain-relieving and anti-inflammatory effects, Peat documented evidence that aspirin inhibits the formation of inflammatory prostaglandins from polyunsaturated fats, supports mitochondrial function, has anti-cancer properties, and protects the liver. He advocated for regular low-dose aspirin use, particularly for people consuming modern PUFA-rich diets.

Peat was critical of the medical profession's ambivalent relationship with aspirin, noting that its effectiveness against cancer, Alzheimer's, and heart disease has been repeatedly demonstrated but downplayed in favor of more profitable drugs. He emphasized taking aspirin with food to protect the stomach and using smaller, more frequent doses rather than large single doses.

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