Dhea
109 sourcesDHEA (dehydroepiandrosterone) is a protective steroid hormone that declines sharply with age — one of the most reliable biomarkers of aging. Ray Peat noted that DHEA opposes cortisol, supports immune function, protects the brain, and has anti-cancer properties. He viewed the DHEA-to-cortisol ratio as an important indicator of the body's stress status.
Peat recommended DHEA supplementation for older individuals, typically 5-15mg for women and 10-25mg for men, noting that it is converted to both androgens and estrogens in tissues. He emphasized that DHEA works best in the context of adequate thyroid function and progesterone, and that supplementing DHEA without addressing these can lead to imbalances.
Key Positions
- DHEA declines sharply with age — one of the most reliable aging biomarkers
- Opposes cortisol's catabolic effects on tissues
- Supports immune function and has anti-cancer properties
- The DHEA/cortisol ratio indicates overall stress and aging status
- Supplemental doses: 5-15mg for women, 10-25mg for men
- Converted to androgens and estrogens in tissues — context dependent
- Works best alongside adequate thyroid and progesterone
Sources
109 items-
One Radio Network: Thyroid, PUFAs, OJ, and Sugar
Ray Peat interview/radio show on Tue Feb 19 2019 from One Radio Network -
One Radio Network: Fats and Questions
Ray Peat interview/radio show on Thu Jan 24 2019 from One Radio Network -
Ask the Herb Doctor: Skin Cancer
Ray Peat interview/radio show on Fri Nov 16 2018 from Ask the Herb Doctor -
calcium phosphate authoritariansim eugenics and cia spymaster allen dulles
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Ask the Herb Doctor: Critical Thinking in Academia
Ray Peat interview/radio show on Fri Aug 17 2018 from Ask the Herb Doctor -
optimizing the environment with ray peat
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Ask the Herb Doctor: Progesterone vs Estrogen, Listener Questions (Part 1)
Ray Peat interview/radio show on Fri Mar 16 2018 from Ask the Herb Doctor -
Ask the Herb Doctor: Language and Criticism, Estrogen (Part 1)
Ray Peat interview/radio show on Fri Jun 16 2017 from Ask the Herb Doctor -
Ask the Herb Doctor: Endocrinology (Part 2)
Ray Peat interview/radio show on Fri Apr 21 2017 from Ask the Herb Doctor -
Ask the Herb Doctor: The Precautionary Principle (Part 1)
Ray Peat interview/radio show on Fri Jan 20 2017 from Ask the Herb Doctor -
safe supplements
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carbon dioxide redox balance and the ketone body ratio
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Ask the Herb Doctor: Exploring Alternatives
Ray Peat interview/radio show on Fri May 20 2016 from Ask the Herb Doctor -
Politics & Science: Biochemical Health
Ray Peat interview/radio show on Wed Mar 11 2015 from Politics & Science -
Ask the Herb Doctor: Nitric Oxide
Ray Peat interview/radio show on Fri Nov 21 2014 from Ask the Herb Doctor -
Ask the Herb Doctor: Field Biology
Ray Peat interview/radio show on Fri Sep 19 2014 from Ask the Herb Doctor -
heart brain cancer and hormones
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Ask the Herb Doctor: Vaccination II
Ray Peat interview/radio show on Fri Jul 18 2014 from Ask the Herb Doctor -
It's Rainmaking Time: Energy-Protective Materials
Ray Peat interview/radio show on Mon Jun 02 2014 from It's Rainmaking Time -
Ask the Herb Doctor: Memory, Cognition and Nutrition
Ray Peat interview/radio show on Fri May 16 2014 from Ask the Herb Doctor -
Politics & Science: William Blake and Art's Relationship to Science
Ray Peat interview/radio show on Wed Feb 26 2014 from Politics & Science -
Ask the Herb Doctor: Questions and Answers
Ray Peat interview/radio show on Fri Jan 17 2014 from Ask the Herb Doctor -
ELUV: Effects of Stress and Trauma on the Body
Ray Peat interview/radio show on Wed Jan 01 2014 from ELUV -
dr peat answers questions regarding health diet and nutration part one
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Voice of America: Water
Ray Peat interview/radio show on Mon Sep 09 2013 from Voice of America