Respiration
244 sourcesRespiration in Ray Peat's framework refers not just to breathing but to the entire process of cellular oxygen utilization — the mitochondrial electron transport chain that converts food energy into ATP. He followed the lineage of Albert Szent-Györgyi and Otto Warburg in viewing respiratory efficiency as the fundamental measure of biological health. When cells respire efficiently, they produce CO2 and water; when respiration fails, they shift to glycolysis, producing lactic acid.
Peat emphasized that breathing patterns matter — hyperventilation reduces CO2 levels, paradoxically reducing oxygen delivery to tissues (Bohr effect). He recommended calm, relaxed breathing and addressing the metabolic factors that drive hyperventilation (low CO2, anxiety, metabolic acidosis).
Key Positions
- Cellular respiration (mitochondrial oxidative phosphorylation) is the foundation of health
- Efficient respiration produces CO2 and water; impaired respiration produces lactic acid
- Hyperventilation reduces CO2, paradoxically reducing tissue oxygenation
- Thyroid hormone is the primary driver of respiratory enzyme activity
- PUFAs damage the respiratory chain by incorporating into cardiolipin
- The respiratory quotient (CO2 produced / O2 consumed) indicates fuel source and efficiency
- Breathing exercises should focus on retaining CO2, not just deep breathing
Sources
244 items-
Ask the Herb Doctor: Antioxidant Theory and the Continued War on Cancer
Ray Peat interview/radio show on Fri Sep 16 2016 from Ask the Herb Doctor -
Ask the Herb Doctor: The Metabolism of Cancer
Ray Peat interview/radio show on Fri Jul 15 2016 from Ask the Herb Doctor -
the origins of authoritarianism with ray peat
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carbon dioxide redox balance and the ketone body ratio
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Ask the Herb Doctor: Exploring Alternatives
Ray Peat interview/radio show on Fri May 20 2016 from Ask the Herb Doctor -
Ask the Herb Doctor: Allergy
Ray Peat interview/radio show on Fri Mar 18 2016 from Ask the Herb Doctor -
mitochondria and mortality
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ray peat and bud weiss on ketogenic diets
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Ask the Herb Doctor: Iodine, Supplement Reactions, Hormones, and More
Ray Peat interview/radio show on Fri Feb 19 2016 from Ask the Herb Doctor -
ray peat bud weiss and misha sakharoff on co2 keto etc
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Ask the Herb Doctor: Current Trends on Nitric Oxide
Ray Peat interview/radio show on Fri Oct 16 2015 from Ask the Herb Doctor -
Ask the Herb Doctor: Longevity and Nootropics
Ray Peat interview/radio show on Fri Aug 21 2015 from Ask the Herb Doctor -
Politics & Science: Biochemical Health
Ray Peat interview/radio show on Wed Mar 11 2015 from Politics & Science -
Ask the Herb Doctor: Uses of Urea
Ray Peat interview/radio show on Fri Feb 20 2015 from Ask the Herb Doctor -
Ask the Herb Doctor: Digestion and Emotion
Ray Peat interview/radio show on Fri Jan 16 2015 from Ask the Herb Doctor -
Ask the Herb Doctor: You Are What You Eat (2014)
Ray Peat interview/radio show on Fri Dec 19 2014 from Ask the Herb Doctor -
Ask the Herb Doctor: Nitric Oxide
Ray Peat interview/radio show on Fri Nov 21 2014 from Ask the Herb Doctor -
heart brain cancer and hormones
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Ask the Herb Doctor: Vaccination I
Ray Peat interview/radio show on Fri Jun 20 2014 from Ask the Herb Doctor -
It's Rainmaking Time: Energy-Protective Materials
Ray Peat interview/radio show on Mon Jun 02 2014 from It's Rainmaking Time -
Ask the Herb Doctor: Diabetes II and How to Restore and Protect Nerves
Ray Peat interview/radio show on Fri Mar 21 2014 from Ask the Herb Doctor -
Politics & Science: William Blake and Art's Relationship to Science
Ray Peat interview/radio show on Wed Feb 26 2014 from Politics & Science -
Ask the Herb Doctor: Diabetes I
Ray Peat interview/radio show on Fri Feb 21 2014 from Ask the Herb Doctor -
Ask the Herb Doctor: Hashimoto's, Antibodies, Temperature and Pulse
Ray Peat interview/radio show on Fri Nov 15 2013 from Ask the Herb Doctor -
Voice of America: Water
Ray Peat interview/radio show on Mon Sep 09 2013 from Voice of America